Exosome Therapy
Signalling molecules applied to support regeneration, most often alongside microneedling.
What is Exosomes?
Exosome preparations are applied topically, most often immediately after microneedling so they pass the outer layer of skin.
Exosomes are extracellular vesicles that carry signalling molecules between cells. Applied to the skin or scalp, they are used to support the regenerative response, calm inflammation and improve tone. In practice they are most often paired with microneedling, which creates the channels that allow them past the outer layer where topical products otherwise stop — the needling opens the route and the exosomes amplify the healing that follows. We treat the face and neck for tone and laxity, and the scalp to support follicle health alongside PRP. This is an area of active development in aesthetic medicine, and we would rather set expectations conservatively at consultation than oversell what the evidence currently supports.
What are exosomes?
Exosomes are extracellular vesicles — very small packages that cells release to carry signalling material to other cells. In practice they are used as a topical preparation applied to the skin, and the intention is to support the skin’s own repair and regeneration signalling. Their most common use here is immediately after microneedling, and the reason is mechanical: intact skin is an effective barrier, and a preparation applied to an untreated surface does not get far past it. The channels created by microneedling provide a window during which topical application can reach beyond the outer layer, which is why the two treatments are paired in the same appointment rather than offered separately. Applied to unbroken skin, an exosome preparation is doing considerably less.
What is exosome therapy used for?
Overall skin quality is the usual target — tone, texture, and the general condition of the skin rather than any single feature. It is also used on the scalp alongside other hair treatments, and on the neck, where skin is thinner and responds differently from the face. Because it is applied rather than injected, it addresses the surface and its healing response, not volume loss and not muscle movement; anyone whose concern is a hollow or a line of expression needs a different treatment. It is generally used as part of a plan rather than alone, most often following microneedling, and results develop over the weeks after treatment as the skin turns over. Your clinician will say where it fits for your skin and whether it is worth adding.
How does exosome therapy compare with PRP?
The most practical difference is the source. PRP is made from your own blood, drawn and spun during the appointment, which means no external material and a treatment whose effect depends on your own healing response. Exosome preparations are supplied rather than made from you, so no blood draw is needed and the appointment is shorter and simpler. Both are used to support skin repair, both are commonly paired with microneedling, and both work gradually rather than immediately. Which is preferred depends on the treatment plan, on whether a blood draw is appropriate or wanted, and on the clinician’s judgement for the concern being treated. They are also sometimes used at different points in the same course rather than being an either-or decision.
Medically reviewed by Dr. Sherwin Hariri, MD, Medical Director & Chief Longevity Physician. Last reviewed August 2026.
This page is for information only and is not medical advice. Suitability for any treatment is determined at consultation.
2 treatments in this category
Exosome Treatment - Face
Topical or injected exosomes to support skin regeneration, calm inflammation and improve tone.
Exosome Treatment - Neck
Exosome treatment targeting laxity and texture on the neck.
Common questions
What are exosomes?
Extracellular vesicles that carry signalling molecules between cells. In aesthetic treatment they are used to support the skin's regenerative response and calm inflammation.
Why are exosomes combined with microneedling?
Microneedling creates channels through the outer layer of skin, which is where most topical products stop. The needling provides the route in; the exosomes amplify the healing response it triggers.
Also consider
Microneedling
Controlled micro-injury that prompts the skin to rebuild — over a course, not a single session.
Learn more →PRP
Your own platelets and growth factors, drawn and processed in clinic at the time of treatment.
Learn more →Hair Restoration
Scalp injections and microneedling to support follicle health and hair density.
Learn more →
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